A postdoctoral research position is available in the field of bioinformatics/genetics within the laboratory of Dr. Wilson Liao, Professor and Vice Chair of Research in Dermatology at the University of California, San Francisco. The Liao Lab conducts research on the genetics and genomics of inflammatory skin disease. Current projects include: large-scale genetic analysis of psoriasis and hidradenitis suppurativa, single cell RNA-seq, and pharmacogenetics
Responsibilities
We are seeking a candidate with an interest in bioinformatics, genetics, precision medicine, immunology, and molecular biology. The ideal applicant will have experience with analysis of gene expression, genotyping data, sequencing data, and genome-wide association studies.
The successful applicant will work on a research team to conduct experiments, perform data analyses, and implement novel approaches relevant for genetic studies of skin diseases. The applicant will play a major role in determining new research directions and in drafting manuscripts and presenting results at professional meetings.
Qualifications
The applicant should hold an M.D., Ph.D., or equivalent degree. This position requires a highly motivated individual with excellent written and verbal communication skills.
Publications
- Liu J, Chang HW, Huang Z, Nakamura M, Sekhon S, Ahn R, Munoz-Sandoval P, Bhattarai S, Beck KM, Sanchez IM, Yang E, Pauli M, Arron ST, Fung-Leung W, Munoz E, Liu X, Bhutani T, North J, Fourie AM, Rosenblum MD, Liao W. Single cell RNA-seq of psoriatic skin identifies pathogenic Tc17 subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer. J Allergy Clin Immunol. 2020 December. 2020 Dec 9;S0091-6749(20)31702-4.
- Lowe MM, Naik HB, Clancy S, Pauli M, Smith KM, Bi Y, Dunstan R, Gudjonsson JE, Paul M, Harris H, Kim E, Shin US, Ahn R, Liao W, Hansen SL, Rosenblum MD. Immunopathogenesis of hidradenitis suppurativa and response to anti-TNF-α therapy. JCI Insight. 2020 Oct 2;5(19):e139932. PMID: 32841223.
- Chang HW, Yan D, Singh R, Liu J, Lu X, Ucmak D, Lee K, Afifi L, Fadrosh D, Leech J, Vasquez KS, Lowe MM, Rosenblum MD, Scharschmidt TC, Lynch SV, Liao W. Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization. Microbiome. 2018 09 05; 6(1):154. PMID: 30185226.
- Yin X, Low HQ, Wang L, Li Y, Ellinghaus E, Han J, Estivill X, Sun L, Zuo X, Shen C, Zhu C, Zhang A, Sanchez F, Padyukov L, Catanese JJ, Krueger GG, Duffin KC, Mucha S, Weichenthal M, Weidinger S, Lieb W, Foo JN, Li Y, Sim K, Liany H, Irwan I, Teo Y, Theng CT, Gupta R, Bowcock A, De Jager PL, Qureshi AA, de Bakker PI, Seielstad M*, Liao W*, Ståhle M*, Franke A*, Zhang X*, Liu J*. Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. Nat Commun. 2015; 6:6916. *Jointly supervised.
For more information, visit: https://liaolab.ucsf.edu
Interested candidates should contact Dr. Wilson Liao at wilson.liao@ucsf.edu or at (415) 476-8364.
Application deadline: Ongoing